Osteomalacia from Chronic use of Anticonvulsant Medication



- Discussion:
    - rickets or osteomalacia may occur from most anticonvulsants;
    - disorder is common and may be present in upto 15% of pts;
    - syndrome is dangerous because of increased sensitivity of central nervous system that occurs with lowering of serum Ca concentration;
    - disorder can be corrected by administration of 1,25-dihydroxyvitamin D



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Thursday, August 23, 2012 10:54 am