Osteocyte


- See:
      - osteoblasts and osteoclasts

- Discussion:
    - osteocyte is mentioned as possibly having resorptive capabilities;
    - it is the most numerous type of bone cell and is derived from an osteoblasts that is not longer synthesizing collagen;
    - osteocytes were once considered to be dormant, metabolically inactive cells;
    - this is now evidence that they can synthesize collagen, control bone mineralization within their lacunae, and possibly carry out bone resorption;
    - resorption:
           - when exposed to parathyroid hormone, osteocytes can secrete enzymes which begin to disolve the osteoid;
           - w/ hyperparathyroidism, Pagets disease, or disuse osteoporosis, osteocytes may be involved in the excessive bone resorption



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, September 13, 2011 12:45 pm