Foot and Ankle International
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Wheeless' Textbook of Orthopaedics

Orthopaedic Care of the Diabetic Patient



- See: General Orders

- Effects on Musculoskeletal System:
    - diabetic foot pathology:
            - vascular pathology:
            - diabetic charcot foot and ankle:
            - neuropathic ulceration:
    - diabetic osteomyelitis
            - experimental evidence that suggests that gram positive bacteria thrive in hyperglycemic state and
                    that gram negative bacteria grow less well in a hyperglycemic serum;
            - this may explain why diabetic patients are more prone to staph infections;
    - diabetic skeletal muscle necrosis: (tumoriform focal muscular degeneration);


- Management of Hyperglycemia:
    antidiabetic agents
    DKA
    hyperosmalar non ketotic coma
    insulin iv infusion
    sliding scale
    types of insulin
    - preop insulin management:
            - 1 unit of insulin disposes of about 8 gm of glucose;
            - 1 unit of glucose should decrease blood glucose by about 50;
            - most operative patients can be maintained in the 120 to 180 blood glucose range w/ regular insulin infusion rate set at 1.0 unit/hour and 2.0 U/hour;
            - note: make the distinction between IDDM and NIDDM
                  - IDDM: pt must receive insulin on a routine schedule and must not be be placed solely on a sliding scale;
                  - NIDDM: pt may be placed solely on Sliding Scale;


- Diabetic Hypertensive Patient:
      - Ca channel blockers may adversely affect Insulin secretion;
      - Diuretics and Beta blockers also have problems;
      - Consider ACE to be the 1st choice for therapy;






American Association of Clinical Endocrinologists
Centers for Disease Control
First Aid Manual - 1
First Aid Manual - 2
Iowa Family Practice Handbook - 1
Iowa Family Practice Handbook - 2
Merck Manual




References

Hyperglycemia in the Hospital Setting.




Original Text by Clifford R. Wheeless, III, MD.