Fibrinogen


- Discussion:
     - precursor of structural protein fibrin & is composed of duplicate sets of three chains (Aalpha, Bbeta, and gamma) linked by disulfide bonds;
     - peptide-bond cleavage of fibrinopeptide A and fibrinopeptide B yields soluble fibrin;
     - fibrin rapidly polymerizes into fibrin strands, ultimately forming fibrin clot that mechanically impedes blood loss



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Monday, December 19, 2011 1:01 pm