- See -
Captopril -
Antihypertensives - for
HTN, CHF; ACE; - Adult: w/
Diuretics initially 2.5mg/day PO titrated to BP; - Adult w/ no diuretic then intial dose: 0.5mg/day PO titrated to BP; - Max dose = 40mg/day divided dose; - Injection dose: 0.625 mg to 1.25mg IV q6hr over 5 min; - titrate to effect (SBP) by 0.625 mg increments; - when patient is ready for PO form, switch to
Captopril (10 times IV dose);
- Precautions: - intital dose may give symptomatic hypotension, esp w/
Diuretics; - attempt to d/c diuretics 2-3 days before intiating ACE; - contraindicated with impaired renal function or renal artery stenosis; - d/c if laryngeal edema/angioedema occurrs; - may cause cough, and note that the vasotec is preferable to
Captopril for patients with collagen vascular dz;
