Ortho-Preferred

Diazepam / Valium



- Discussion:
     for anxiety, muscle spasm, status epilepticus, sedation preop;
     Adult: Stat elepticus: 0.2-.5mg/kg/dose IV q15-30 min. w/ maximum dose of 30mg; 0.2-0.5 mg/kg/dose PO / 0.05-0.2 mg/kg/dose IV;
     Peds: status epilepticus: < 5yrs: 0.2-0.5 mg/kg/dose IV q15-30 min up to max of 5 mg; >5 yrs may administer to max of 10 mg; sedation: 0.04-0.2 mg/kg/dose q2-4hr IM/IV to max of 0.6 mg/kg in 8hrs;
     Will usually achieve peak level 1hr after dosing w/ t/2 of 20-50 hr;w/ a duration of up to 12 hrs.
     If necessary may repeat in 1hr, otherwise repeat in 3-4hr;;
     Alternative for seizure: Valium at a rate of 2 mg/min IV, until the seizure stops or to max dose of 20mg (10 min);
     Anxiety, Muscle Spasm: 2-10mg PO/IM q3-4hr prn;
     Preop 5-10mg PO/IM 20-30 min before the procedure;
     Can be given IV just prior to the procedure;
     Dont exceed >5mg/min IV-may getRespiratory arrest; Have Ambu bag at bedside; Absorption of IM dose can be erratic;
     Contraindicated with acute narrow angle glaucoma,alcohol, CNS depressants;
     Note has one active metabolite;
     Note not compatable w/ Phenytoin in same IV site;
           Supplied: SR caps: 15mgs; tabs: 2mg, 5mg, 10mg,; solution 5 mg/5ml; injection 5mg/ml



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, July 3, 2012 1:18 pm