- See:
Priorities of Weaning from Ventilatory Support Vital Capacity > 15 cc/kg Negative Inspiratory Force < -25 cm H2O Respiratory
rate < 30 Spontaneous
Tidal vol > 5 cc/kg (may not be important) 48 % false negative prediction of outcome; PaO2 > 300 mm Hg on FiO2 of 100%; Trial of room air @CPApp4fvn[CPAP: -
IMV rate of 0, FiO2 of 21%, & CPAP of 5 cm H20; After 1/2 hr, extubate if: - PaO2 > 55 torr (FiO2 = 21%); - Ventilatory
rate < 30 - pH > 7.35 - pCO2 < 45 torr 94 % predictive of patient tolerating extubation;
Priorities of Weaning from Ventilatory Support: - appearance: no apprehension or diaphoresis - consciousness: alert and responsive to verbal commands - mean arterial pressure > 80 mm Hg - mean left atrial pressure (
wedge) less than 18 mm Hg - minmal bleeding - normal body temperature - FiO2 less than 0.5 w/ a pO2 > 80 mm Hg -
PEEP < 5 cm or less - no untreated arrhythmia - spontaneous tidial vol > 5 ml/kg - spontaneous vital capacity > 10 ml/kg - spontaneous respiratory
rate less than 30 / min - negative inspiratory force greater than 25 cm - mean time to extubation can be decreased by as much as 41% using a protocol, which can also reduce arterial blood gas sampling rates; - PaO2 maintained > 80 mm Hg - FiO2 set to give a pO2 of 150 mm Hg in the first two hours - FiO2 set to give a pO2 of 110 mm Hg thereafter; - pCO2 maintained < 45 mm Hg - pH maintained between 7.35 and 7.50
Original Articles: A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation.