Dose (mg)
Interval
Specificity
Acebutolol
Atenolol
50-100
daily
Cardioselective
Esmolol
Labetolol
200
bid
Metoprolol
50-200
bid
Cardioselective
Nadolol
40-240
daily
Nonselective
Pindolol
10-30
bid
Nonselective
Propanolol
10-80
qid
Nonselective
Timolol
10-30
bid
Nonselective
- Cautions and Interactions:
- when discontinuing beta blockers, it is necessary to taper dose;
- aspirin (by inhibiting prostacycline) will decrease the effectivness of class II agents;
- beta-Adrenergic-receptor antagonists reduce the renal plasma flow & glomerular filtration rate & should
therefore be avoided in pts with renal impairment;