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Wheeless' Textbook of Orthopaedics
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Bleeding secondary to Platlet Abnormalities


- Evaulation: - Patient's Temperature: - hypothermia causes platlet dysfunction and increased bleeding time; - Treatment - platlets (6-8 units at a time); - One unit of platlets will increase platlet count by 1000; - Check 1hr post Platlet Count; - Dilutional Thrombocytopenia; - RBC transfusion or IV fluid therapy; - Treat with Platlet transfusions as needed; - Must transfuse 8 units of platlets for every 10-12 units of pRBC's transfused; - Misc: - Von Willebrand's dz: Treat with Cryoprecipitate or DDAVP; - Acquired Platlet dysfunction: w/ Uremia try conjugated estrogens; - Note: TTP: Platlet transfusion is Contraindicated; ----------------------------------------- Review Article: Seminars in Medicine of the Beth Israel Hospital, Boston: Molecular And Cellular Biology Of Blood Coagulation.



Original Text by Clifford R. Wheeless, III, MD.