- See:
Soft Tissue Menu:
- Discussion:
- high grade sarcomas of vascular origin;
- occur most often in middle aged persons;
- when the tumor arises in bone, it frequently extends up and down the
bone w/ distinctive pattern of "soap bubble" lesions;
- sub-types:
-
hemangioendothelioma - more common in bone than in soft tissue
-
hemangiopericytoma - more common in soft tissue than in bone;
- Diagnostic Studies:
- permeative, invasive nature of lesion is evident on CT &
MRI;
- bone scans show marked radioisotope uptake;
- Histology:
- fine neoplastic capillaries course thru background of endothelial cells;
- w/ hemangioendothelioma, pattern is dominated by neoplastic endothelial cells;
- Treatment:
- angiosarcomas require either a wide surgical margins + adjuvant XRT;
- radical amputation is also an option;
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Skeletal-Extraskeletal Angiomatosis. A Clinicopathological Study of
Fourteen Patients and Nosologic Considerations.
