Urokinase

- See: Thrombolytic Therapy: Pharmocological Agents for Vascular Surgery
- Dose: 
- load w/ 4,400 units/kg IV bolus overe 10 min;
- load w/ 50,000 units IV bolus into the occluded vessel, then infuse at 50,000 units/hr; 
- maintenance dose: 4,4000 units/kg for 12-24 hrs 


Two urokinase dose regimens in native arterial and graft occlusions: initial results of a prospective, randomized clinical trial

Increased limb salvage with intraoperative and postoperative ankle level urokinase infusion in acute lower extremity ischemia.

 




Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Monday, December 19, 2011 1:20 pm