SOMOS Annual meeting
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presents
Wheeless' Textbook of Orthopaedics

Urokinase


- See: Thrombolytic Therapy: Pharmocological Agents for Vascular Surgery; - Dose: - load w/ 4,400 units/kg IV bolus overe 10 min; - load w/ 50,000 units IV bolus into the occluded vessel, then infuse at 50,000 units/hr; - maintenance dose: 4,4000 units/kg for 12-24 hrs; ------------------ Two urokinase dose regimens in native arterial and graft occlusions: initial results of a prospective, randomized [1mclinical trial [m. Increased limb salvage with intraoperative and postoperative ankle level urokinase infusion in acute lower extremity ischemia.



Original Text by Clifford R. Wheeless, III, MD.