- Increased: - Volume depletion, CHF, Adrenal Insufficiency, DM,
SIADH, Increased proteins (nephrosis) (upto 1.050); - If markedly increased (1.040-1.050), Suspect artifact or excretion of radiographic contrast media;
- Decreased: - DI, Pyelonephritis, Glomerulonephritis, Waterload w/ Nl Renal Function;
- Misc: - Specific gravity varies inversely with urine excretion - In some conditions this relationship is affected: - Diabetes: increased volume; increased specific gravity; - HTN: normal volume; decreased specific gravity; - Early chronic renal disease: increased volume; decreased spec. gravity; - Interfering Factors: - SG highest in the AM sample - Elevated with Excess water loss - contrast media in contrasts (and dextrin): false positive;