Type III Collagen



- See: Collagen Discussion:

- Discussion:
    - in Dupuytren's, there is an increase in type III collagen (which is similar to scar tissue);
          - normal fascia is mostly of type I collagen;
    - Ehlers-Danlos Syndrome:
          - see collagen disorders;
          - at least 9 types of Ehlers-Danlos syndrome have been defined;
          - mutations in Type III collagen may result in a of lethal form of Ehlers-Danlos syndrome;
          - most severe form is known as Type IV and is characterized by sudden rupture of large arteries or intestines;
                 - since the strength of large arteries depends largely on fibrils of type III collagen, it is possible that some forms of type IV Ehlers-
                        Danlos syndrome result from mutations in the type III collagen gene



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, September 13, 2011 12:43 pm