Total hip arthroplasty in Gaucher's disease. Long-term prognosis

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Goldblatt-J; Sacks-S; Dall-D; Beighton-P Department of Human Genetics, University of Cape Town, South Africa. Clin-Orthop. 1988 Mar(228): 94-8 Avascular necrosis of the femoral head is a cause of morbidity in patients with Gaucher's disease. Total hip arthroplasty (THA) is recommended, but there is controversy about the long-term value of this procedure. In eight patients treated with 15 THAs, 11 (73%) have remained fully mobile and asymptomatic up to 14 years following surgery. These long-term follow-up observations are evidence in favor of THA for treatment of hip joint problems associated with Gaucher's disease.