- See:
-
Timentin
-
Pen Family
-
AntiPseudo
- There are small differences in the pattern of activity of these
agents against gram-negative organisms.
Ticarcillin is two to four
times more active than carbenicillin against P. aeruginosa;
- less active against gram positive organisms;
- Dose: 2-24gm q 4hr Injection, or for serious systemic infections
200-300 mg/kg/24hr IV in divided doses;
- for complicated
UTI: 150-200 mg/kg/day IV in 4-6 divided doses;
- for
UTI: 1gm IV/IM q6hr;
- Used alone note Gram Neg Resistance;
* Dosing Regimens for Patients w/ Renal Insufficiency: (Dose for 70 kg
Adult {gm/dosing interval in hrs CrCl:>80:3/4; CrCl:50-79:3/4;
CrCl:30-49:2/4; CrCl:10-29:2/6-8;
- 60-70% of drug will be excreted in to urine (w/ nl RF(x));
- Peds: 200-300 mg/kg/day q6hr
- Supplement dose after Dialysis:
Hemo: 3 gm
CAPD: 3 gm
