Studies in management of the contaminated wound. 3. Assessment of the

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effectiveness of irrigation with antiseptic agents. Edlich RF. Custer J. Madden J. Dajani AS. Rogers W. American Journal of Surgery. [JC:3z4] 118(1):21-30, 1969 Jul. - irrigation of contaiminated wounds with either 70% ETOH, aqueous iodine, povidone-iodine provided significant protection against dev. of infect. in contaminated wounds; - the inflammatory response of the contaminated wounds after treatment with these agents suggests that the microorganisms within the tissue are overwhelmed with minimal damage to tissue; - saline solution: irrigation of the contaminated wound with saline solution provided no significant protection against the development of infection;