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Wheeless' Textbook of Orthopaedics
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State of Calcium in Body Fluids





- See:
      - Physical Properties of Calcium:
- Discussion:
      - the concentration of   ionic calcium in blood must be kept below solubility
            product of Ca phosphate salt, & it is also important that additional calcium
            is reversibly complexed with plasma proteins;
      - total calcium concentration in plasma is approx l0mg/l00 ml, whereas ionized
            portion is slightly > 50% of this amount;
      - most clinical problems of either hypo- or hypercalcemia are result of continued
            net movement of Ca in only one direction between cell membranes and
            extracellular fluid;
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Calcium flux and endogenous calcium content in isolated mammalian
  growth-plate chondrocytes, hyaline-cartilage chondrocytes, and
  hepatocytes.



Original Text by Clifford R. Wheeless, III, MD.