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Wheeless' Textbook of Orthopaedics
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Skin Preparation Agents

- See: Methods to Prevent Infection:


- Skin Preparation Agents:
   - alcohol:
        - rapid significant reduction in skin microbial counts is major effect desired;
   - techni-care:
   - iodophors: 
   - ioban draping: (3M™ Ioban™)
         - Risk for infection after anterior cervical fusion: prevention with iodophor-impregnated incision drapes.
         - Prevention of wound contamination using DuraPrep solution plus Ioban 2 drapes.
         - The prevention of wound contamination by skin organisms by pre-op application of an iodophor impregnated plastic adhesive drape.
         - Prevention of bacterial colonization of wounds at operation: comparison of iodine-impregnated ('Ioban') drapes with conventional methods.

    - chlorohexidine: (Chloraprep)





The antimicrobial effectiveness of operative-site preparative agents: a microbiological and clinical study.

Damage to tissue defenses by a topical anesthetic agent.

Influence of preoperative showers on staphylococcal skin colonization: a comparative trial of antiseptic skin cleansers.

The impact of preoperative skin disinfection on preventing intraoperative wound contamination.

Effect of antiseptics, ultraviolet light and lavage on airborne bacteria in a model wound.

Bacteriologic evaluation of electric clippers for surgical hair removal.

The impact of preoperative skin disinfection on preventing intraoperative wound contamination.

Bacterial skin contamination after surgical preparation in foot and ankle surgery.

Efficacy of Surgical Preparation Solutions in Foot and Ankle Surgery.

Preoperative Skin Preparation of the Foot and Ankle: Bristles and Alcohol Are Better.









Original Text by Clifford R. Wheeless, III, MD.