Developmental Dysplasia of the Hip
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Wheeless' Textbook of Orthopaedics

Sed Rate in THR



- See: General Discussion: Erythrocyte Sedimentation Rate

- Discussion:
    - elevation of sed rate can be a reliable test for diagnosis of infected THR;
    - greater than 85% of pts w/ infection about THR have elevated sed rate
            & 79 % have a rate of more than 50 mm / hour;
    - in the report by Lachiewicz et al (JBJS 1996), the mean sed rate was 80 mm/hr;
    - screening levels:
            - if 30 to 35 mm is used as a threshold for infection, then the sensitivity rate will
                    range from 61-88% and the specificity rate will range from 96 to 100 %;

- Normal Values:
    - sed rate in pts undergoing an uncomplicated THR reaches maximum of
            64 mm / hour on 6 postoperative day;
    - rate averaged 50 mm / hour until 3 weeks after surgery and thereafter
            slowly decreased to 30 mm hour over course of year;
            - after 3 weeks, sed rate that remains higher than 40 mm / hour
                    suggests that pt has infection until proved otherwise;
    - polymethylmethacrylate does not appear to have significant effect on
            sed rate, and increase that occurs after uncomplicated THR is related to
            surgical intervention;




Erythrocyte sedimentation rate in infection of total hip replacements.

The erythrocyte sedimentation rate following exchange of infected total hips.





Original Text by Clifford R. Wheeless, III, MD.