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Wheeless' Textbook of Orthopaedics
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Methods to Prevent Surgical Infection:

    - Antibiotics: 
          - prophylactic antibiotics 
          - local antibiotic delivery 
          - antibiotic beads
          - addition of antibiotics to cement 

    - Skin Preparation:
          - topical agents:
                - skin prep agents
                - topical antimicrobials 

    - Reduction in OR Contamination: 
          - surgeon hygiene
                  - double gloving:
                          - Glove perforation in pediatric orthopedic practice.
                          - Glove perforation in ortho and trauma surgery. A comparison between single, double indicator gloving and double gloving with 2 regular gloves.
                          - Glove perforation and contamination in primary total hip arthroplasty

          - operating room hygiene:
                    - Intraoperative Contamination Influences Wound Discharge and Periprosthetic Infection.
                    - Unnecessary hospital infection control practices in Thailand: a survey.
                    - The hygienic significance of operating lights
                    - Transfer of bacteria between biomaterials surfaces in the operating room-An experimental study. 
                    - Microbial colonization of tourniquets used in orthopedic surgery. 

   wound management

    - techniques to make the patient more resistant to infection:
          - perioperative oxygen
                - references:
                         - Supplemental Perioperative Oxygen to Reduce the Incidence of Surgical-Wound Infection
                         - The effect of differing ambient oxygen tensions on wound infection.
                         - Assessment of perfusion in postoperative patients using tissue oxygen measurements.
                         - Local heat increases blood flow and oxygen tension in wounds.
                         - Direct measurement of wound and tissue oxygen tension in postoperative patients.
                         - Special Topic: Hyperbaric Oxygen Therapy in Plastic Surgery: A *Review* Article.
                         - Oxygen as an isolated variable influences resistance to infection.      
                         - Oxygen as an antibiotic. A comparison of the effects of inspired O2 concentration and antibiotic administration on in vivo bacterial clearance.         
                         - The dynamic properties of tissue oxygen in healing flaps.    
                         - Tissue oxygenation, anemia, and perfusion in relation to wound healing in surgical patients.
                         - The influence of epidermal thickness on transcutaneous oxygen pressure measurements in normal persons.
                         - High-dose magnesium sulfate attenuates pulmonary oxygen toxicity. 
          - normothermia:
                         - Perioperative Normothermia to Reduce the Incidence of Surgical-Wound Infection and Shorten Hospitalization 

 




Original Text by Clifford R. Wheeless, III, MD.