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Wheeless' Textbook of Orthopaedics
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Prazosin/Minipreq


- Discussion: - for HTN; - Alpha blocker with some direct smooth muscle relaxation: - Dosing: - Initial: 1mg PO bid to tid (watch out for syncope); - Maintenance dose: 6-15 mg/day given in 2-3 divided doses; - Maximun daily dose: 20 mg/day; - Precautions: - syncope may occur w/ dose > 2 mg; - hypotension may occur with concomitant use of Beta blockers; ------------------------------------ Postoperative urinary retention associated with total hip and total knee arthroplasties.



Original Text by Clifford R. Wheeless, III, MD.