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Wheeless' Textbook of Orthopaedics
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Piroxicam / Feldene



- Discussion:
    - NSAIA;
    - Rheumatoid and Osteoarthritis, Ankylosing spondylitis;
    - Dosage: 10-20mg PO qd (has an extended half life);
    - therapeutic response should only be assessed after two weeks or more of continuous treatment;
    - may cause diarrhea;
    - Contraindicated in patients with syndrome of bronchospasm, nasal polyps,
              angioedema precipitated by ASA or other NSAIA;
    - Use with caution in patients   with a h/o upper GI bleeding, heart failure,
              renal insufficiency, liver dysfunction, hypertension and in patients
              with other conditions predisposing to fluid retention;




The effect of piroxicam on the metabolism of isolated human chondrocytes.




Original Text by Clifford R. Wheeless, III, MD.