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Wheeless' Textbook of Orthopaedics

PHENYLEPHRINE/NEO SYNEPHRINE


- Discussion: - for treatment of vascular failure in shock, hypersensitivity, or drug induced hypotension; - used to overcome paroxysmal SVT; - blood pressure maintenance during spinal anesthesia; - alpha agonist vasoconstrictor: - Dosage: - mild hypoTN: 2-5mg IM or SQ elevatesBP for 2 hrs; - 0.1-0.5 mg IV given as slow IV injection; - Dilution: - 10mg/250ml D5W; for severe hypotension or shock: - initiate continuous infusion at 100-180 ug/min, after BP stabilizes maintain rate of 40-60ug/min;



Original Text by Clifford R. Wheeless, III, MD.