presents
Wheeless' Textbook of Orthopaedics

Non AG Hyper Cl Acidosis: Diff dx determined by changes in Serum Potassium





Hyperkalemia
  - Determination of the serum K is especially useful in the evaluation
      of hyperchloremic metabolic acidosis.   Infusions of mineral
      acids result in elevated serum K levels because of the shift in K+ out
      of cells in exchange for H+ entry.   Thus, hyperalimentation,
      NH4 Cl, CaCl2 ingestion, and Cholestyramine administration,
      all cause a hyperkalemic Non Anion Gap Acidosis.   In addition,
      hypoadosteronism results in a defect in K+ excretion, leading to
      Hyperkalemia.
  - Hyperchloremic acidosis associated w/ hypokalemia:
      - Gastrointestinal HCO3 losing entities, including Diarrhea,
          pancreatic drainage, biliary drainage, uterosigmoidostomy, or
          obstructed ileal loop, distal RTA (I), and proximal
          RTA (II).




Original Text by Clifford R. Wheeless, III, MD.