- See:
Class IV Agents:
- Discussion:
- for vasospastic or chronic stable
Angina;
Hypertensive crisis;
- inhibits coronary artery spasm;
- given Sublinngual for
HTN crisis;
- combine with Nitrates for intractable
Angina;
- HA are common initially; note reflex
Tachycardia;
- direct & indirect arterial vasodilator (greater than
diltiazem)
-
minimal cardiodepressant action;
- may be safely used w/ Beta antagonists and note that use with
Beta blockers may reduce palpitations, flushing, and HA;
- dose not affect
Digoxin levels;
- Adult Dosing:
- begin at 5-10 mg PO q8hr;
- usual dose: 10-40 mg PO tid;
- maximum: 180mg/day;
- increase from 10 mg to 30 mg over a 3 day period;
-
Procardia XL:
- for
HTN or
Angina: 30-60 mg PO qd;
- max dose = 90 mg;
- Contraindications:
-
w/
Aortic Stenosis, Obstructive cardiomyopathy, or severe myocardial
depression/hypotension;
References for Nifedipine:
