Ortho-Preferred

Neurilemoma/ Schwannoma

 - Discussion:
    - nerve sheath tumor which arises from schwann cells;
    - commonly develop in cranial nerves (most often the 8th nerve);
    - most often develops in sensory nerves;
    - mass grows slowly and usually does not cause symptoms unless it grows within a confined space such as the tarsal tunnel;
    - asked patient about any family history of type-I (peripheral) neurofibromatosis;

- Classification:
    -
classic  type is the most common (less common include: ancient, cellular, plexiform, epitheliod, glandular, pacinian, melanotic)
    - histology shows interlacing fascicles (Antoni A areas) and pallisading of nucleii, which are hypercellular;
    - less cellular zones (Antoni B areas)
    - S100 protein immunohistochemistry will confirm the diagnosis;

- Treatment:
    - in most cases, the neurilemoma can be shelled out from the nerve w/ blunt dissection


Benign nerve tumours of the hand (excluding wrist)  

Definition of the Target Sign and Its Use for the Diagnosis of Schwannomas.


Peripheral nerve sheath tumors of the foot and ankle.



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, November 3, 2015 8:38 am