Developmental Dysplasia of the Hip
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Wheeless' Textbook of Orthopaedics

Natural History of DDH



- See: DDH - Main Discussion

- Discussion:  
    - 95-98% of DDH cases are possibly reversible;
    - 2% of DDH cases may have teratologic dislocation which is generally not reversible;
    - less than 2% of infants will have a positive Barlow's test (dislocatable hip);
            - 60% will normalize w/ no treatment after 1 month;
            - 88% will normalize w/ no treatment after 2 months;
            - this comes to about 1-2 patients per 1000 which have a true DDH which
                  will go on to produce the pathological changes of DDH;
            * Barlow TG. 1962.
    - when radiographic findings are added to clinical findings the number of
            good results (w/ no treatment) diminish significantly;
            - 22% will normalize w/ no treatment;
            - 39% will retain some dysplastic features;
            - 13% will be subluxed;
            - 26% will remain dislocated;
            * Coleman, 1968.
    - concave acetabulum cannot develop without concentric force exerted by the reduced femoral head;
    - w/ time, there is progression of pathologic features which include development of
            intra-articular impediments to reduction develop and muscule groups about
            the hip become shortened and contracted;
            - an untreated hip dislocation becomes more difficult to reduce causing
                  Ortolani's test to becomes negative;
            - normal acetabular development ceases and the potential for the acetabulum
                  to resume normal growth onced reduced is diminished;
                  - this decrease in remodeling potential can occur after age one year;
    - CE angle may have limited predictive value for DJD, when patients w/ subluxation
            are excluded from consideration (subluxation is probably the most important risk factor);

- Physical Exam:

- Natural History in Adults:
    - development of false acetabulum;
         
          - 76% will have poor result w/ well developed false acetabulum;
          - 48% will have poor result w/ moderately developed or absent acetabulum;
                - if femoral head does not articulate w/ the acetabulum, degenerative changes will
                      not occur and range of motion will generally be maintained;
    - unilateral dislocation:
          - flexion-adduction deformity of the affected hip;
          - gait disturbance which is quite noticable;
          - leg length inequality;
          - valgus deformity of the knee which can lead to DJD of lateral compartment;
          - scoliosis;
          - contra-lateral "normal" hip is often found to have acetabular dysplasia;
          - it may not be appropriate to apply standard hip functional studies (such as
                Harris Hip Score) to DDH patients w/ complete dislocation;
                - these studies are geared to the problems of elderly patients rather than
                        the functional considerations of younger patients;
          - 48% will have poor result w/ moderately developed or absent acetabulum;
                - if femoral head does not articulate w/ the acetabulum, degenerative changes will not
                        occur and range of motion will generally be maintained;
          - even if degenerative changes do not develop, patients will often fatigue
                when they attempt to walk distances more than several hundred meters;
    - bilateral dislocation:
          - when both hips are dislocated, perineal space is widened, & greater trochanters are more prominent than normal;
          - buttocks are broad & flat, & lumbar spine is hyper-lorddotic;
          - child with bilateral hip dislocation has a waddling gait;
          - back pain may develop due to hyperlordosis;
          - objective functional studies are lacking, but it is generally felt that complete bilateral dislocation
                causes relatively mild functional limitations as compared to the complications associated w/ forced
                reduction (AVN and DJD);
    - subluxation:
          - by definition implies not only subluxation but also acetabular dyplasia;
          - Shenton's line is broken;
          - clear progression of DJD based on age of patient and degree of subluxation;
          - prognosis is worse in females;
          - early radiographic changes include sclerosis along the wt bearing portion of the acetabulum;
          - early clinical findings include groin pain;
          - females begin to complain of pain in mid 30's (depending on CE angle);
                - degenerative changes usually develop around age 45 yrs;
                - often DJD will not appear until 5 yrs or more after onset of symptoms;
                - once degenerative changes begin, they can progress quickly;
          - males begin to complain of pain in mid 40's-50's;
                - radiographic changes may not develop until age 70 yrs;
    - acetabular dysplasia:
          - by definition subluxation is not present;
          - Shenton's line is intact;
          - has a better prognosis than subluxation and progression to DJD is less predictable than w/ subluxation;
          - can be an incidential radiographic finding;
          - prognosis is worse in females;
          - often DJD will not appear for 10 yrs or more after onset of symptoms;
          - in the report by Kiril Mladenov, M.D et al (Journal of Pediatric Orthopaedics 2002; 22(5):607-612), the authors that the management
                  of Management of clinically stable hips with an increased age-related acetabular index (AI) remains controversial;
                  - 4 patterns of evolution were observed:
                  - type 1 (25 hips) had rapid progression to normal range in the first 2 years;
                  - type 2 (19 hips) had slow improvement, with AI values reaching the normal range between 4 and 11 years;
                  - type 3 (20 hips) had improved hip morphology with persistence of minor deviations from the normal values;
                  - type 4 (4 hips) showed no improvement.
          - references:
                  - Acetabular Dyplasia in the Adult.




- Case Example: of untreated DDH:
   
    - 14 yr old female w/ untreated DDH who presented w/ progressive hip pain;
          (patient's mother declined formal orthopaedic treatment, despite the advice of 3 different orthopaedists);




Congenital dysplasia of the hip in the Navajo infant.
    Coleman SS.   Clinical Orthopaedics and Related Research. 1968. 58: 179.

Untreated congenital hip dysplasia in the Navajo.
    Pratt WB, Freiberger RH, Arnold WD. Clinical Orthopaedics and Related Research. 1982; 162: 69.

Congenital Hip Dislocation.   Long Range Problems, Residual Signs, and Symptoms After Successful Treatment.
    S.L. Weinstein MD   Clinical Orthopaedics and Related Research. No. 281: 69.

The Natural History of Congenital Dislocation of the Hip. A Critical Review.
    JH Wedge MD FRCS and MJ Wasylenko MD   Clinical Orthopaedics and Related Research. No. 137: 155.

Early Diagnosis and Treatment of Congenital Dislocation of the Hip.
    Barlow TG.   JBJS (Br). 1962. 44: 292.

Natural history of congenital hip dislocation (CDH) and hip dysplasia.

The prognosis in untreated dysplasia of the hip. A study of radiographic factors that predict the outcome.

The natural history of congenital disease of the hip.








Original Text by Clifford R. Wheeless, III, MD.