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Wheeless' Textbook of Orthopaedics
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Nail Bed Biopsies




- Discussion:
    - indicated for the diagnosis of nail tumors or unexplained deformities;
    - may be performed using "punch method" or thru open nail bed biopsy;
    - open biopsies should use transverse incisions in the nail matrix and
          longitudinal incisions in the nail bed;
    - biopsy material should not be handled directly, but rather should be
          removed with a needle;

- Nail Matrix Biopsy:
    - if possible avoid biopsy thru the nail matrix, and especially avoid
          biopsy of the more proximal matrix (as this contributes to the
          surface of the nail);
    - biopsy is indicated for pigemented longitudinal streaks (which are
          suspicious for melanoma;
          - in this case mark the proximal nail fold to assist w/ locating
              the pathologic matrix (after the nail is removed);
    - open biopsies should use transverse incisions in the nail matrix and
          longitudinal incisions in the nail bed;












Original Text by Clifford R. Wheeless, III, MD.