Developmental Dysplasia of the Hip
Tracking Pixel
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Wheeless' Textbook of Orthopaedics

Mixed Venous O2 / VO2-DO2


- Sampling of Mixed Venous O2: - Shows changes in Arterial oxygenation as the Cardiac Output changes; - Allows calculation of AVo diff and Shunt: (for Respiratory Failure); - PVo2 < 30 mm Hg, prognosis is poor; - Discussion: - normally the Svo2 is about 68 to 77%, w/ a PaO2 to 40 mm Hg; - if Vo2 is constant, reductions in Svo2 values should reflect increases in oxygen demand or decreases in Cardiac Output or arterial O2 content; - decrease in Svo2 of > 10%, or a fall in Svo2 to less than 60% usually indicates inadequate oxygen delivery to the tissues; - Svo2 less than 50% is often associatted with hypotension; ------------------------ Relationship between oxygen consumption and oxygen delivery during anesthesia in high-risk surgical patients. Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high-risk surgery. Oxygen consumption and resting metabolic rate in sepsis, sepsis syndrome, and septic shock. Incommensurate oxygen consumption in response to maximal oxygen availability predicts postinjury multiple organ failure.



Original Text by Clifford R. Wheeless, III, MD.