Metoclopramide/Reglan/ Clopra

- Diabetic Gastroparesis:

- 10mg PO 30min AC and HS for2-8 weeks prn;


- GI Reflux: 
- 10-15mg PO 30min AC and HS; maximum duration of therapy is 12 weeks; 
- Prophylaxis of N/V in Cancer Chemotherapy; 
- IV infusion 1-2mg/kg diluted in 0.9% saline and given slowly (over 15min) 30 min before cancer chemotherapy and repeated q2hr x 2 doses; - then q3hr x 3 doses;

- Facilitated of Small Bowel Intubation
- 10mg IV (undiluted) given over 2min; 
- dystonic rxn common, treat with IV benadryl 50mg; 
- avoid concmitant use of other drugs likely to cause extrapyramidal rxn; 
- sedation is another side effect; 
- this syndrom is age related, give antihistamines and/or lorazapem 
- contraindicated with GI obstruction, perforation, hemorrhage, or any other GI condition where increased GI motility is contraindicated 

Pharmacological evacuation of the stomach with metoclopramide.

Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Friday, December 16, 2011 3:29 pm