SOMOS Annual meeting
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presents
Wheeless' Textbook of Orthopaedics

Metoclopramide/Reglan/ Clopra


- Diabetic Gastroparesis: - 10mg PO 30min AC and HS for2-8 weeks prn; - GI Reflux: - 10-15mg PO 30min AC and HS; maximum duration of therapy is 12 weeks; - Prophylaxis of N/V in Cancer Chemotherapy; - IV infusion 1-2mg/kg diluted in 0.9% saline and given slowly (over 15min) 30 min before cancer chemotherapy and repeated q2hr x 2 doses; - then q3hr x 3 doses; - Facilitated of Small Bowel Intubation: - 10mg IV (undiluted) given over 2min; - Precautions: - dystonic rxn common, treat with IV benadryl 50mg; - avoid concmitant use of other drugs likely to cause extrapyramidal rxn; - sedation is another side effect; - this syndrom is age related, give antihistamines and/or lorazapem - contraindicated with GI obstruction, perforation, hemorrhage, or any other GI condition where increased GI motility is contraindicated; ---------------------- Pharmacological evacuation of the stomach with metoclopramide.



Original Text by Clifford R. Wheeless, III, MD.