- See:
-
Isocarboxazid/Marplan
-
Tranylcypromine/Parnate
-
Phenelzine/Nardil
- Discussion:
- can potentiate the depressive effects of narcotics;
- can cause fever and seizures when administered to a patient receiving
MAOI;
- the pressor effect of indirectly acting agents such as ephedrine may be greatly exagerated;
- the traditional recommendations are that
MAOI be discontinued 2 weeks before surgery;
- anticholinergic agents be avoided whenever possible;
- meperidine should definitely be avoided, whereas
fentanyl or morphine appear to be suitable during Hanesthesia;
- enflurane or isoflurane are preferred over halothane because of reduced arrhythmogenic potential;
- due to the possibility of hypotension associated with spinal and epidural anesthesia and the subsequent requirement for
basopressors general anesthesia is preferred.
