- Discussion:
- indicators for poor outcome:
- encroachment of tumor on the popliteal neurovascular bundle;
- pathologic fracture with contamination of multiple tissue compartments;
- local recurrence from previous surgery;
Preoperative chemotherapy for osteogenic sarcoma: Selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy.
Rosen G, Caparros B, Huvos AG:
Cancer 1982;49:1221-1230.