Lavage of septic joints in rabbits: effects of chondrolysis

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Daniel-D; Akeson-W; Amiel-D; Ryder-M; Boyer-J J-Bone-Joint-Surg-Am. 1976 Apr; 58(3): 393-5 Septic joints were produced in rabbits which were then treated with systemic procaine penicillin. One group of animals also had surgical lavage at four and seven days after bacterial inoculation. In the infected joints there was a significant loss of hexosamine by five days and of collagen by nine days. Lavage delayed the loss of collagen.