SOMOS Annual meeting
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Wheeless' Textbook of Orthopaedics

Isosorbide Dinitrate/Isordil


- causes venodilation; - Acute Angina: 2.5-10mg PO or SL prn q5-10 min; - more than 3 doses should not be given within 15-30 min; - Angina prophylaxis: 5-60 mg PO tid; - or try initially: SL tab: 2.5-10 mg q2-3hr, - or Chew tab: 5-10mg q2-3hr; or Swallowed tab: 5-40mg q6hr; - controlled release cap or tab: 40-80mg q8-12hr; - must titrate dose to clinical response; - nitrates should not be given chronically q6hr because of tolerance;



Original Text by Clifford R. Wheeless, III, MD.