- See:
Inotropic Agents - Discussion: - use of this med is limited to temporary control of significant
Bradycardia that is refractory to atropine; - is the only one of the major inotropes which can decrease pulmonary vascular resistance; - this is useful in patients w/ pulmonary
HTN (esp. mitral valve patients) & patients w/ acute Right Heart Failure;
- Precautions: - it is not indicated in the treatment of electromechanical dissociation; - it is extremely arrhythmogenic, causing Ventricular arrhythmia's w/ even moderate dosing;
- avoid excessive HR especially with acute
MI; - vasodilation with decrease in blood pressure;
- contraindicated with
Tachycardia, pulse >130 may induce ventricular arrhythmias;
- Dosage: - infusion is prepared by adding 1-2 mg of isoproterenol to 250-500 ml of D5W and administering at 1-20 ug/min and titrate to HR; - may begin therapy with small ?(0.2-0.5mg) IV dose; - then begin IV infusion; - Cardiac arrest and Cardiac Dysrhythmias: - Dilute .2mg (1ml of 1:5000 sol) to 10ml with .9% NaCl of D5W, and inject IV 0.02-0.06mg (1-3ml); - Shock: 1-4ug/min IV infusion, titrateto effect, or better try:
