Isocarboxazid/Marplan


- Isocarboxazid is a MAOI 
- usual dose is 30 mg/day; 
- Isocarboxazid should be used with caution in combination w/ other monoamine oxidase inhibitors, tricyclic antidepressants, Carbamazepine, or cyclobenzaprine; 
- GEA and isocarboxazid may produce a combined hypotensive effect. 
- anticholinergic agents be avoided whenever possible; 
- meperidine should definitely be avoided, whereas fentanyl or morphine appear to be suitable during Hanesthesia; 
- enflurane or isoflurane are preferred over halothane because of reduced arrhythmogenic potential; 
- due to the possibility of hypotension associated with spinal and epidural anesthesia and the subsequent requirement for basopressors general anesthesia is preferred.



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Thursday, June 23, 2011 9:29 pm