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Wheeless' Textbook of Orthopaedics
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Inflammatory Bowel Disease



- See: Spondyloarthropathies:

- Discussion:
    - associated with a peripheral arthritis, which reflects activity of bowel disease;
    - frequently associated with erythema nodosum;
    - large joint oligoarthritis occurs in 10 to 20 % of pts, usually during flares of the bowel disease;
    - fevers, synovitis, & vesiculopustular skin lesions may follow intestinal bypass surgery;
    - some patients will develop spondylitis which acts independently of   bowel dz;
    - associated conditions:
            - pyoderma gangrenosum;

- Labs:
    - most affected patients are HLA-B27 positive;
    - cultures of blood and genital secretions are negative;












Original Text by Clifford R. Wheeless, III, MD.