Orthopaedic Jobs

IMIPRAMINE/TOFRANIL



    for depression; childhood enuresis; trycyclic antidepressant; Adult:
Hospitalized: Start at 100mg/24hr in divided doses; can increase over several weeks to 250-300mg/24hr; 
Outpatient: Maintainance of 50-150mg/24hr in divided doses; not to exceed 300 mg/24hr; 
Do not use with MAO inhibitors; less sedation that with Amitriptyline;  
Note Side Effects: Sedation: ++;Insomnia: 0; Anticholinergic: ++;Orthostatic Hypotension: +++; Nausea: 0 
Peds: Enuresis: >6hr old: Initially 10-25 mg PO qhs; increase by 10-25 mg increments every 1-2 weeks until the desired effect or maximum dose of 2.5 mg/kg/day 
Antidepressant: 1.5 mg/kg/24hr PO or IM in 3 DD with max of 5mg/kg/24hr



Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, July 3, 2012 1:54 pm