for depression; childhood enuresis; trycyclic antidepressant; Adult:
Hospitalized: Start at 100mg/24hr in divided doses; can increase over
several weeks to 250-300mg/24hr; Outpatient: Maintainance of
50-150mg/24hr in divided doses; not to exceed 300 mg/24hr; Do not use
with MAO inhibitors; less sedation that with
Amitriptyline;
Note Side
Effects: Sedation: ++;Insomnia: 0; Anticholinergic: ++;Orthostatic
Hypotension: +++; Nausea: 0; Peds: Enuresis: >6hr old: Initially 10-25 mg
PO qhs; increase by 10-25 mg increments every 1-2 weeks until the desired
effect or maximum dose of 2.5 mg/kg/day; Antidepressant: 1.5 mg/kg/24hr
PO or IM in 3 DD with max of 5mg/kg/24hr;
