Hyperosmalar Non Ketotic Coma

- Treatment of Hyperosmolar Non Ketotic Coma: 
- Infusion of Normal Saline to restore volume 
- Reg Insulin 10-25 units IV 
- Insulin drip 5-10 units/hr until Serum Glucose < 500 mg/dl; 
- Insulin given IV has plasma t 1/2 of 5 min and a biologic effect for about 20 min; 
- thus, even brief period of insulin deficiency, esp in patient w/ IDDM, may allow rapid deterioration in metabolic control

Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, June 7, 2011 3:59 pm