* Adults: Parental: 0.001-0.002 mg/kg/dose IV, may repeat in 1 to 2 hrs;
1-2 micrograms/kg/dose IM/IV: 100 micrograms = 10 mg Morphine.
Pre-op: 0.005-0.01 mg/kg IM 30-60 min before surgery;
Children (2-12 yrs): Parental: 0.02-0.03 mg/20-25 lbs (10 kg);
* IM: onset at 7-8 min; duration 1-2 hrs;
IV: peak effect at 5 min; duration 10-20 min.
* Sedative effects last up to 4 hrs.
* Less emetic effect, less sedation, and less histamine release than other narcotic analgesics;
* Contraindications include hypersensitivity and MAO Rx;
* Adverse reactions include respiratory depression, muscular rigidity, and bradycardia;
* Administer naloxone for respiratory depression
Pharmacokinetics of continuous infusions of fentanyl in critically ill children.
Original Text by Clifford R. Wheeless, III, MD.
Last updated by Data Trace Staff on Tuesday, July 3, 2012 1:33 pm