Ewing's sarcoma. Prognostic factors, disease control, and the reemerging

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role of surgical treatment. AU: O'Connor-MI; Pritchard-DJ AD: Mayo Graduate School of Medicine, Mayo Clinic, Rochester, MN 55905. SO: Clin-Orthop. 1991 Jan(262): 78-87 AB: Advances in the treatment of Ewing's sarcoma have been dramatic. Present treatment protocols control local disease by radiotherapy, surgery, or both; systemic spread is limited by aggressive multiagent chemotherapy. In patients with localized osseous Ewing's sarcoma, five-year survival rates now range from 54% to an estimated 74%. With late relapse not uncommon, control of the primary lesion is critical to long-term survival. Several studies now show improved local control and possibly improved survival of patients with surgical treatment of primary osseous Ewing's sarcoma.