Clinical Signs for DVT

• exam may be unreliable but positive findings should not be ignored
• calf tenderness, swelling, fever, & increased pulse rate may be present
• suggestive exam features for pulmonary embolism
• sudden decrease in O2 saturation
• tachypnea, cyanosis, and hypoxia
• pulmonary consolidation, pleural effusion, wheeze, and cor pulmonale
• new onset tachydysrhythmia (usually atrial fibrillation)

Menu

• Overview
• Diagnosis
• Risk Reduction
  • THA
  • TKA
  • Trauma, pelvic fractures, and extremity fractures
• Risks
• Treatment
  • Anticoagulants
  • Low molecular weight heparins
  • Vitamin K antagonists
  • Thrombolytics

• pulmonary embolus
• hypercoagulable states
• coagulation pathway

References

• NICE recommends rivaroxaban (Xarelto®) to prevent blood clots in people who have had a heart attack - NICE 3/25/15
• Bayer Discloses Encouraging Data on Anticoagulant Xarelto
• Bayer happy with Rivaroxaban (Xarelto®) trial results
• New oral anticoagulants in the treatment of acute venous thromboembolism - a systematic review with indirect comparisons.
• Length of stay and economic consequences with rivaroxaban vs enoxaparin/vitamin K antagonist in patients with DVT and PE: findings from the North American EINSTEIN clinical trial program.
• Rivaroxaban for the treatment of venous thromboembolism. A "real-life" perspective in 103 patients
• Treatment of patients with acute deep vein thrombosis and/or pulmonary embolism: efficacy and safety of non-VKA oral anticoagulants in selected populations.
• Images in Clinical Medicine. Phlegmasia Cerulea Dolens.
• Clinical problem-solving. A sinister development--a 35-year-old woman presented to the emergency department with a 2-day history of progressive swelling and pain in her left leg, without antecedent trauma.