- Digoxin metabolism is Inhibited by: - Erythromycin - Tetracycline -
quinidine may double Dig levels; -
Verapamil and Amiodarone -
Hypokalemia and
HypoMagnesemia and Hypoxia will potentiate toxicity, - Digoxin bioavailability is decreased by: - cholestyramine, -
KAOLIN-pectin - antacids; - Can cause
heart block; - Toxicity = N/V, diarrhea, HA, GI symptoms, anorexia, pyschiatric, fatique, visual lesions (yellow-green halos around lights) & cardiac arrthymia;