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Wheeless' Textbook of Orthopaedics

Cyclobenzaprine/Flexeril




- Adjunct to rest and physical therapy for relief of muscle spasm associated
    w/ acute painful musculoskeletal conditions; CNS relief of muscle spasm;
- Adult: 10mg PO tid; Do not use for longer than 2-3 weeks; sedative and
    anticholinergic properties;
- Contraindicated with MAOI use, Tricyclics, during acute recovery from MI,
- Contra w/ hyperthyroidism, CHF, dysrhythmias, heart block, conduction
      disturbances; Flexeril may enhance the effects of barbiturates, alcohol,
      and other CNS depressants;
      - use with caution in patients with hx of urinary retention, angle closure
            glaucoma, increased intraocular pressure and in patients taking
              anticholinergic medications;



Original Text by Clifford R. Wheeless, III, MD.