- Discussion:
    - aspirin & other nonsteroidal antiinflammatory drugs block biosynthesis of prostaglandins and thromboxane A(sub 2) by inhibiting 
           cyclooxygenase enzyme;
    - ASA covalently acetylates cyclooxygenase, inhibiting it irreversibly, whereas other NSAIDs act reversibly on the cyclooxygenase

Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Wednesday, April 25, 2012 3:17 pm