Bretylium/Bretylol


* Adrenergic blocker and Antiarrhythmic; 
* For Acute Treatment of Resistant VF or VT (LIDOCAINE, Defibrillation, PROCAINAMIDE Failure) 
* Dose: 5-10 mg/kg IV rapid injection (1 minute); 
* may repeat w/ 10mg/kg IV push repeated q15-30 min w/ 10mg/kg 
* (max = 30 mg/kg) - given undiluted w/ life threatening arrhythmia, but w/ hemodynamically unstable pts dilute w/ 50ml D5W and infuse slowly IV over 8-10 min to reduce acute hypotensive effects; 
* Maintenance: 1-4 mg/min IV infusion; 
* Supplied: Injection 50mg/mL; 
- Caution: 
* Should rpaidly reduce dose and discontinue in 3-5 days;

* Note: N/V associatted withrapid IV push; 
* transient rise in BP seen initially; 
* Hypotension most frequent adverse effect and occurs with in the first hour of treatment




Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Wednesday, December 14, 2011 3:45 pm