Augmentation of critical skin flap survival following ibuprofen therapy
Nichter LS. Sobieski MW. Edgerton MT. Annals of Plastic Surgery. [JC:5vb] 16(4):305-12, 1986 Apr. Much research effort has attempted to identify pharmacological agents that will augment random skin flap survival. Unfortunately, the vast majority of these agents have been administered preoperatively, and as such their routine use is not often justified. Ibuprofen administered in the postoperative period significantly augments random skin flap survival in the rat.
Original Text by Clifford R. Wheeless, III, MD.
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