The Hip: Preservation, Replacement and Revision

Antihemophilic Factor VIII

- for treatment of classical hemophilia A to replace missing clotting factor to correct or prevent bleeding episodes of perform emergency or elective surgery; 
- Dosage: 1 AFH unit/kg increases Factor VIII concentration in body by approx 2%; 
- Prophylaxis of spontaneous hemorrhage = 5% normal; 
- Hemostasis following trauma or surgery = 30% normal; 
- Major Soft tissue bleeding = 80 - 100% normal; 
- Head injuries or major surgery = 100% + normal; 
- Note: Not effective in controlling bleeding of patients with von Willebrand's dz

Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Wednesday, December 14, 2011 3:07 pm