SOMOS Annual meeting
Tracking Pixel
presents
Wheeless' Textbook of Orthopaedics

Antihemophilic Factor VIII


- for treatment of classical hemophilia A to replace missing clotting factor to correct or prevent bleeding episodes of perform emergency or elective surgery; - Dosage: 1 AFH unit/kg increases Factor VIII concentration in body by approx 2%; - Prophylaxis of spontaneous hemorrhage = 5% normal; - Hemostasis following trauma or surgery = 30% normal; - Major Soft tissue bleeding = 80 - 100% normal; - Head injuries or major surgery = 100% + normal; - Note: Not effective in controlling bleeding of patients with von Willebrand's dz;



Original Text by Clifford R. Wheeless, III, MD.