Ampicillin (Amcil, Omnipen)


- See: Penicillin Family

- Discussion:
    - ampicillin is usually given IV as unasyn vs. amoxicillin which is given orally;
    - for treatment of suseptible gram negatives (Shigella, Salmonella, E. coli, H. influenza, P.mirabilis, N. gonorrhea) and gram positives (streptococci);
    - adult: 500mg - 2gm PO, IM, or IV q6hr;
    - peds:
          - term infants: 150-200 mg/kg/24hr divided q6-8hr IV or IM;  
          - > 1 month and children: 150-400 mg/kg/24hr divided q4-6hr IM or IV; 50-100 mg/kg/24hr divided 6hr PO upto 250 mg/dose;
    - meningitis: 400 mg/kg/24hr divided q4-6hr IV;
    - renal dosing:
    - GFR > 90: 500 mg q6hr; GFR 60-90: q8hr; 10-50: q12 hr; <10: q12-24 hr;
    - supplied: capsules 250 mg, 500 mg; suspension 100 mg/ml, 125 mg/5ml, 250 mg/5ml; powder for injection: 125 mg, 250mg, 500mg, 1gm, 2gm, 10gm vials





Original Text by Clifford R. Wheeless, III, MD.

Last updated by Clifford R. Wheeless, III, MD on Friday, February 8, 2013 8:12 pm