- for mild pain, HA, F, Nonnarcotic analgesic, Antipyretic,
- Adult: 350-650-1000mg PO q4-6hr; Max: 3.2 gm per 24hr;
- OD may cause hepatoxicity (often delayed), antidote is N-acetylcystiene;
- No antiplatlet activity; No antiinflamitory property Caution with patients with Glucose 6 Phos defficiency;
- Contraindications: Acetominophren hypersensitivity;
- overdosage presents early as Nausea, Vomiting, and malaise, and presents late as clinical and labratory evidence of hepatotoxicity;
- Do not use charcol to treat OD;
- Acetyl-cystein (Muco Myst) may be used depending on the time after ingestion;
- Supplied: Tabs 325 mg, 500 mg; elixir 120 mg/5 ml; t/2=1-3hrs;
- Supplied: Caps: 325, 500 mg; tabs: 325, 500, 625;
- Peds: 10-15 mg/kg/dose PO or PR q4-6hrs;
- Peds: 0-3mo:  40mg/dose; 4-11mo:  80mg/dose; 12-24mo: 120mg/dose;
       4-5yr: 240mg/dose; 6-8yr: 320mg/dose; 9-10yr:  400mg/dose;
       11-12yr: 480mg/dose;
    Adult:1-2 tab q3-4hr PRN
    Codeine content in #1=7.5mg, in #2=15mg, in #3=30mg, in #4=60mg
    Onset in 30min; Peak in 45-90min;Duration for 4-6hr;t1/2=3-4hr;
    Peds: Acetaminophen 10 mg/kg/dose; Codeine: 0.5-1.0 mg/kg/dose q4-6hr;
    Supplied: Tabs, caps

Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee

Original Text by Clifford R. Wheeless, III, MD.

Last updated by Data Trace Staff on Tuesday, July 3, 2012 11:50 am