- for mild pain, HA, F, Nonnarcotic analgesic, Antipyretic,
- Adult: 350-650-1000mg PO q4-6hr; Max: 3.2 gm per 24hr;
- OD may cause hepatoxicity (often delayed), antidote is N-acetylcystiene;
- No antiplatlet activity; No antiinflamitory property Caution with patients
with Glucose 6 Phos defficiency;
- Contraindications: Acetominophren hypersensitivity;
- overdosage presents early as Nausea, Vomiting, and malaise, and presents
late as clinical and labratory evidence of hepatotoxicity;
- Do not use charcol to treat OD;
- Acetyl-cystein (Muco Myst) may be used depending on the time after
ingestion;
- Supplied: Tabs 325 mg, 500 mg; elixir 120 mg/5 ml; t/2=1-3hrs;
- Supplied: Caps: 325, 500 mg; tabs: 325, 500, 625;
- Peds: 10-15 mg/kg/dose PO or PR q4-6hrs;
- Peds: 0-3mo:
40mg/dose; 4-11mo:
80mg/dose; 12-24mo: 120mg/dose;
4-5yr: 240mg/dose; 6-8yr: 320mg/dose; 9-10yr:
400mg/dose;
11-12yr: 480mg/dose;
ACETAMINOPHREN w/ CODEINE (TYLENOL #1,2,3,4);
Adult:1-2 tab q3-4hr PRN
Codeine content in #1=7.5mg, in #2=15mg, in #3=30mg, in #4=60mg
Onset in 30min; Peak in 45-90min;Duration for 4-6hr;t1/2=3-4hr;
Peds: Acetaminophen 10 mg/kg/dose; Codeine: 0.5-1.0 mg/kg/dose q4-6hr;
Supplied: Tabs, caps;
-------------------------------------
Comparison of an antiinflammatory dose of ibuprofen, an analgesic
dose of ibuprofen, and acetaminophen in the treatment of patients
with osteoarthritis of the knee [see comments
